Meet Jeuveau™ (prabotulinumtoxinA-xvfs)—aka the #NEWTOX! Jeuveau™ is a modern-made neurotoxin approved by the FDA to temporarily improve the appearance of frown lines. 1 Jeuveau™ is the first and only product of its kind dedicated exclusively to aesthetics! As the fourth neurotoxin to hit the market (and the only new option in almost a decade), Jeuveau™ is made using a state-of-the-art manufacturing process called Hi-Pure™ technology. 2 Jeuveau™ is the first product from Evolus, and part of its mission to bring a fresh experience and perspective to the aesthetics industry. It’s about time! See full Important Safety Information
JEUVEAU may cause serious side effects that can be life-threatening. Get medical
help right away if you have any of these problems any time (hours to weeks) after
injection of JEUVEAU:
● Problems swallowing, speaking, or breathing, due to weakening of associated
muscles, can be severe and result in loss of life. You are at the highest risk if these
problems are pre-existing before injection. Swallowing problems may last for several
● Spread of toxin effects. The effect of botulinum toxin may affect areas away from the
injection site and cause serious symptoms including: loss of strength and all-over
muscle weakness, double vision, blurred vision and drooping eyelids, hoarseness or
change or loss of voice, trouble saying words clearly, loss of bladder control, trouble
breathing, trouble swallowing.
Do not use JEUVEAU if you: are allergic to any of the ingredients in JEUVEAU (see
Medication Guide for ingredients); had an allergic reaction to any other botulinum toxin
product such as rimabotulinumtoxinB (MYOBLOC®), onabotulinumtoxinA
(BOTOX®/BOTOX® Cosmetic), abobotulinumtoxinA (DYSPORT®), or incobotulinumtoxinA
(XEOMIN®); have a skin infection at the planned injection site; or are a child.
JEUVEAU dosing units are not the same as, or comparable to, any other botulinum.
Tell your healthcare provider about all your muscle or nerve conditions, such as ALS or
Lou Gehrig’s disease, Myasthenia gravis, or Lambert-Eaton syndrome, as you may be at
increased risk of serious side effects including difficulty swallowing and difficulty
breathing from typical doses of JEUVEAU.
Tell your healthcare provider about all your medical conditions, including: any side
effects from botulinum toxin products, including dry eye; breathing, swallowing, bleeding,
or heart problems; plans to have surgery; weakness of forehead muscles; drooping
eyelids; had surgery on your face; are pregnant or breastfeeding or plan to become
pregnant or breastfeed (it is not known if JEUVEAU can harm your unborn baby or
passes into breast milk).
Tell your healthcare provider about all the medicines you take, including prescription
and over-the-counter medicines, vitamins, and herbal supplements. Using JEUVEAU with
certain other medicines may cause serious side effects. Do not start any new medicines
until you have told your healthcare provider that you have received JEUVEAU in the
Especially tell your healthcare provider if you: have received any other botulinum toxin
product in the past and the last 4 months, and exactly which product you received (such
as BOTOX, BOTOX Cosmetic, MYOBLOC, DYSPORT, or XEOMIN).
JEUVEAU may cause loss of strength or general muscle weakness, vision problems, or
dizziness within hours to weeks of treatment with JEUVEAU. If this happens, do not
drive a car, operate machinery, or do other dangerous activities.
JEUVEAU can cause other serious side effects including: allergic reactions (such as
itching, rash, red itchy welts, wheezing, asthma symptoms, or dizziness or feeling faint),
heart problems (such as irregular heartbeat and heart attack), and eye problems
(including dry eye, reduced blinking, and corneal problems). Tell your healthcare provider
or get medical emergency help right away if you experience a serious side effect.
The most common side effects include: headache; eyelid drooping, upper respiratory
tract infection, and increased white blood cell count in your blood.
JEUVEAU is a prescription medicine that is injected into muscles and used in adults for a
short period of time (temporary) to improve the look of moderate to severe frown lines
between the eyebrows (glabellar lines).
The risk information provided here is not complete. For more information about
JEUVEAU, see the full Prescribing Information including BOXED WARNING, and
Medication Guide, visit evolus.com or talk to your healthcare provider.
To report side effects associated with use of JEUVEAU, please call 1-877-EVOLUS1/1-
877-386-5871. You are encouraged to report negative side effects of prescription
drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
Manufactured by: Evolus, Inc., 1027 Garden St., Santa Barbara, CA 93101
©2019 Evolus, Inc. All rights reserved. JEUVEAU is a trademark of Evolus, Inc. All other
trademarks are the property of their respective owners.
REFERENCES: 1. Jeuveau [Package Insert], Santa Barbara, CA: Evolus, Inc.; 2019. 2.
United States Patent: US 9,512,418 B2; Dec. 6, 2016.